Pregnancy in Caesarean Scar: Accurate Diagnosis and Success in Conservative Management

Authors

  • Satrio Budhi Purnomo Resident of Obstetrics and Gynecology, Faculty of Medicine, Andalas University, Dr. M. Djamil Central General Hospital Padang
  • Dovy Djanas Sub Division of Maternal Fetal Medicine, Obstetrics and Gynecology Department, Faculty of Medicine, Andalas University, Dr. M. Djamil Central General Hospital Padang

DOI:

https://doi.org/10.25077/aoj.4.1.114-119.2020

Abstract

Reported case in a woman aged 30 years, with a history of cesarean scar four years ago, diagnosed with gravid two by one gravid 7-8 weeks with gestation on cesarean scar. The patient had a history of accidental trauma two days prior to the complaint of bleeding from the genitals. Several obstetricians have examined but still obtained different results (intrauterine pregnancy and ectopic pregnancy). An accurate diagnosis is critical to the success of the management of a patient with a pregnancy with this life-threatening cesarean scar. With a precise and accurate transvaginal ultrasound examination, the diagnostic criteria with ultrasound on previous surgical scars have been fulfilled in this patient, including an empty uterus, an empty cervical canal image, growth of a gestational pouch in the anterior lower segment of the uterus, and the absence of myometral image between the bladder wall and the gestational pocket. On B-HCG examination, the result was 58,808.70 mlU / mL. Conservative therapy with metrotrexate (MTX) 50 mg / m2 intramuscularly. After giving metrotrexate (MTX) therapy for four times, the results of B-HCG decreased significantly with 21.530, 12 mlU / mL, 2,949.47 mlU / mL, and 593.61 mlU / mL, respectively. After administration of metrotrexate (MTX) therapy, there was a decrease in the size of the gestational bag.

Keywords: Ectopic, Pregnancy, Methotrexate, Cesarean Section

References

Wang HY, Zhang J, Li YN. Laparoscopic management or laparoscopy combined with transvaginal management of type II cesarean scar pregnancy. JSLS 2013;17:263–72

Masuda H, Uchida H, Maruyama T. Successful treatment of atypical cesarean scar defect using endoscopic surgery. BMC Pregnancy Childbirth 2015;15:342.

Jurkovic D, Knez J, Appiah A, Woelfer B, Lawrence A, Salim R, Elson JC. Surgical treatment of Cesarean scar ectopic pregnancy: efficacy and safety of ultrasound-guided suction curettage. Ultrasound Obstet Gynecol 2016;47:511–7.

Birch Petersen K, Hoffmann E, Rifbjerg Larsen C, Svarre Nielsen H. Cesarean scar pregnancy: a systematic review of treatment studies. Fertil Steril 2016; 105: 958-967..

Bignardi T, Condous G. Transrectal ultrasound-guided surgical evacuation of cesarean scar ectopic pregnancy. Ultrasound Obstet Gynecol. 2010. April;35(4):481-485.doi: 10.1002/uog.7596.

Calì G, Timor-Tritsch IE, Palacios-Jaraquemada J,et al. Outcome of cesarean scar pregnancy managed expectantly: systematic review and meta-analysis. Ultrasound Obstet Gynecol. 2018. February;51(2):169-175. doi:10.1002/uog.17568. .

SeowKM , Huang LW, Lin YH , Lin MYS, Tsai YL Hwang JL. Cesarean scar pregnancy: issues in management. Ultrasound Obstet Gynecol. 2004 ; 23: 247–253.

Jurkovic D, Hillaby K, Woelfer B, Lawrence A, Salim R, Elson CJ. First trimester diagnosis and management of pregnancies implanted into then lower uterine segment Cesarean secon sca. Ultrasound Obstet Gynecol.2003; 21: 220–227.

Vial Y, Pegnat P, Hohlfeld P. Pregnancy in a cesarean scar. Ultrasound Obstet Gynecol. 2000;16:592–3. Gonzalez, N, Tulandi, T: Cesarean scar pregnancy: a systematic review. J Minim Invasive Gynecol 2017;24(5):731–738.

Monteagudo A, Carreno C, Timor-Tritsch IE. Saline infusion sonohysterography in nonpregnant women with previous cesarean delivery: the ‘‘niche’’ in the scar. J Ultrasound Med 2001; 20: 1105–1115.

Ash A, Smith A, Maxwell D. Caesarean scar pregnancy. BJOG 2007; 114: 253-263

Bayoglu Tekin Y, Mete Ural U, Balik G, Ustuner I, Kir Sahin F, Guvendag Guven ES. Management of cesarean scar pregnancy with suction curettage: a report of four cases and review of the Lliterature. Arch Gynecol Obstet 2014; 289: 1171-1175.

Rheinboldt M, Osborn D, Delproposto Z. Cesarean sectionscar ectopic pregnancy:a clinical case series. J Ultrasound 2015;18:191–5.

Weilin C, Li J. Successful treatment of endogenous cesarean scar pregnancies with transabdominal ultrasound-guided suction curettage alone. Eur J Obstet Gynecol Reprod Biol 2014; 183: 20-22.

Qian ZD, Weng Y, Wang CF, Huang LL, Zhu XM. Research on the expression of integrin β3 and leukaemia inhibitory factor inthe decidua of women with cesarean scar pregnancy. BMC pregnancy childbirth. 2017;17(1):84.

Gozdemir E, Simavli S. Cesarean Scar Pregnancy: Diagnosis and Treatment. J Nurs Care. 2014;3:182

Fang Q, Sun L, Tang Y, Qian C, Yao X Quantitative risk assessment to guide the treatment of cesarean scar pregnancy. Int J Gynaecol Obstet. 2017;139:78–83.

Timor-Tritsch IE, Monteagudo A, Santos R, Tsymbal T, Pineda G, Arslan AA. The diagnosis, treatment, and follow-up of cesarean scar pregnancy. AMJ.ObsteriaGynecol. 2012: 207:44.e1–44.e13.

Kutuk MS, Uysal G, Dolanbay M, Ozgun MT. Successful medical treatment of cesarean scar ectopic pregnancies with systemic multidose MTX: single-center experience. J Obstet Gynaecol Res. 2014;40(6):1700–6.

Giampaolino P, Della Corte L, Venetucci P, D'Antuono F, Morra I, Nappi C, et al Treatment of asymptomatic uterine rupture of caesarean scar pregnancy in patient with advanced gestational age: case report. J Obstet Gynaecol. 2017; 38(4), pp. 571–572

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Published

2020-01-10

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CASE REPORT