Effect of Virgin Coconut Oil in The Treatment of Leucorrhea Caused by Candida Albicans Infection on Pregnant Women at Hospitals in Padang
DOI:
https://doi.org/10.25077/aoj.5.2.231-240.2021Abstract
Introduction : According to WHO, the prevalence of reproductive health problems in women has reached 33% from all types of diseases. One of the most frequent reproductive health problems is fluor albus. The incidence of candidiasis in pregnant women has doubly increased, especially at third trimester, compared to women who were not pregnant. Candida should be considered a dangerous pathogen in early pregnancy.
Objective : This study compared the number of colonies before and after the administration of virgin coconut oil (VCO) to address vaginal discharge caused by C. albicans infection in pregnant women.
Material and methods : This is an experimental study on 36 pregnant women. Examination of fluor albus is done by applying vaginal swab before and after administration of 1 tablespoon of VCO orally three times a day dan 5cc of VCO was applied on the vagina and vulva for intervention group, meanwhile the control group was not given anything. Statistical analysis to test the significance is done by using T-test.
Results : There was a difference on average number of colonies with higher number of colonies prior to administration (137.17 ± 16.35 vs 122.17 ± 14.42). The average number of colonies at the first examination was 96.06 ± 8.85 colonies and increased at the second examination to 112.89 ± 12.49 colonies.
Conclusion : There was an effect of VCO administration on decreasing the number of colonies in the intervention group (p=0.000), while in control group, there was increasing average number of colonies in the second examination (p=0.000).
Keywords: Candida albicans, fluor albus, pregnant women, virgin coconut oilReferences
Altayyar IA, Alsanosi AS, Osman NA. Prevalence of vaginal candidiasis among pregnant women attending different gynecological clinic at South Libya. Eur. J. Exp. Biol.. 2016;6(3):25–9.
Cunningham, F. G., Patel, Roberts, Zink. Williams Obstetrics.25th Infectious disease. United state. The McGraw-Hill Companies; 2019
Jhon F.Kennedy. Comprehensive Gynecology. 7th edition. Philadepia: library of congress cataloging- in publication. Elsivier.2017
Jackie S, Gilbert D DW. European (IUSTI/WHO) Guideline on the Management of Vaginal Discharge. UK: Department of Genitourinary Medicine.
Filippidi A, Galanakis E, Maraki S, GalaniI, Drogari-Apiranthitou M, Kalmanti M, et al. The effect of maternal flora on Candida colonisation in the neonate. Mycoses. 2014;57(1):43-8.
Shiris N Daftary. Selected topics in obstetrics and gynaecology-3: For postgraudate and practitioner. 2007
Neville F. Hacker, Joseph C. Gambone, Calvin J. Hobel. Hacker & Moore's Essentials of Obstetrics and Gynecology E-Book. Sydney, Australia. 2010
Brooks,G.F.Carrol, K.C.Butel, J. S. Dani morse. Medical microbiology. Salemba Medika. Jakarta.2004.
Wilkins L&. Vaginal infection. 15th ed. India: Berek and Novak’s Gynaecology
Walsh TJ, Hayden RT, Larone DH. Larone's medically important fungi: A guide to identification. New York, 2018
Malcolm D. Richardson, David W. Warnock. Fungal infection: Diagnosis and management. 2003
Mutiawati VK. Pemeriksaan mikrobiologi pada Candida Albicans. Juornal Kedokt Syiah kuala. 2016;16:53-63.
Aring, B. J., Mankodi, P. J., Jasani, J. H. Incidence of vaginal Candidiasis in leucorrhoea in women Attending in OPD of Gynecology and Obstetrics Department. Int J Biomed Adv Res.2012; 3(12): 867–9.
Soong D, Einarson A. Vaginal yeast infections during pregnancy. Can Fam Physician. 2009;55(3):255–6.
Syukur S. Bioteknologi virgin coconut oil dan potensi kandungan zat-zat antibodi dan antimikroba atau virus. Padang: Pusat kajian Bioteknologi Industri dan Biomolekuler Universitas Andalas Padang; 2004.
Widianingrum, D. C., Noviandi, C. T, Salasia SIO. Antibacterial and immunomodulator activities of virgin coconut oil (VCO) against Staphylococcus aureus. Heiyon. 2019;5.
Dewi SS, Aryadi T. Efektifitas virgin coconut oil ( VCO ) terhadap kandidiasis secara invitro. Pros Semin Nas Int. 2010;1(1). doi:10.1016/j.inoche.2014.10.028
Khan MSA et. al. Virulence and pathogenicity of fungal pathogens with special reference to Candida albicans. Berlin Heidelberg: springer-verlag Berlin Heidelberg; 2010.
Nasir M. M, Abllah, Z., Jalaludin A., Azura Shahdan I, Hayati Wan Abd Manan WN. Virgin coconut oil and its antimicrobial properties against pathogenic microorganisms: A review. Adv Heal Sci Res Vol 8 Int Dent Conf Sumatera Utara 2017. 2017. doi:10.2991/idcsu-17.2018.51.4
Kett DH et. al. Candida bloodstream infections in intensive care units : Analysis of the extended prevalence of infections in intensive care unit study. Crit Care Med. 2011;39:665-670
Rebecca Jeanmonod; Donald Jeanmonod. Vaginal Candidiasis (Vulvovaginal Candidiasis). Last Update: April 28, 2020.
Poerwanto S, Hidayat C S. Sintesis lipida terstruktur dari asam laurat dan gliserol dalam pelarut isooktana dengan biokatalis lipase Candida rugosa. Reaktor. 2010;13(1):44
Tjin LD, Setiawan AS, Rachmawati E. Exposure time of virgin coconut oil against oral Candida Albicans. Padjadjaran J Dent. 2016;28(2):89-94. doi:10.24198/pjd.vol28no2.13718
Downloads
Published
Issue
Section
License
Copyright (c) 2021 Andalas Obstetrics And Gynecology Journal
This work is licensed under a Creative Commons Attribution 4.0 International License.
Copyright
Authors who publish with this journal agree to the following terms:
- Authors retain the copyright of published articles and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution 4.0 International License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
License:
Andalas Obstetrics and Gynecology Journal (AOJ) is published under the terms of the Creative Commons Attribution 4.0 International License. This license permits anyone to copy and redistribute this material in any form or format, compose, modify, and make derivatives of this material for any purpose, including commercial purposes, as long as they credit the author for the original work.