From Molar Pregnancy, Thyrotoxicosis, to Pulmonary Hypertension: A Case Report
(1) Medical Doctor Program, Faculty of Medicine, Mulawarman University
(2) Department of Internal Medicine, Abdoel Wahab Sjahranie General Hospital
(3) Department of Cardiology and Vascular Medicine, Abdoel Wahab Sjahranie General Hospital
(4) Department of Obstetrics and Gynecology, Abdoel Wahab Sjahranie General Hospital
(*) Corresponding Author
DOI: https://doi.org/10.25077/aoj.8.1.660-666.2024
Abstract
Background: Molar pregnancy is a benign condition with the dominant symptom being dark brown to bright red bleeding from the vagina. This disease can induce hyperthyroidism and result in pulmonary hypertension. This case report describes a patient who had molar pregnancy with thyrotoxicosis and pulmonary hypertension.
Case: A 30-year-old woman presented with complaints of lower abdominal pain for the last month. The patient feels that her stomach has enlarged in the last 3 months. Other complaints include bleeding and observed bubbles from the birth canal, shortness of breath, and chest pain. The serum cobas β-hCG level of 7954.00 mIU/mL. On abdominal ultrasound examination, vesicles formed a honeycomb appearance, measuring 7.4 cm×5.3 cm. Hematologic laboratory tests revealed low TSH levels (<0.01 μIU/mL), T3 levels of 2.35 ng/ml, and FT4 levels of 2.62 ng/dL. The results of the echocardiography examination showed there is a high probability of pulmonary hypertension.
Conclusion: Molar pregnancy can exacerbate thyrotoxicosis through hCG activity. Smoking and breastfeeding also have similar effects. Consequently, increased thyroid hormone levels can worsen or cause pulmonary hypertension.
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