MANAGEMENT OF HYPERPROLACTINEMIA CAUSED PITUITARY MICROADENOMA
(1) Department of Obstetry and Gynecology, Faculty of Medicine, Andalas University/Dr. M. Djamil, Padang
(2) Subdivision of Fertility and Endocrynology, Department of Obstetry and Gynecology, Faculty of Medicine, Andalas University/Dr. M. Djamil, Padang
(*) Corresponding Author
DOI: https://doi.org/10.25077/aoj.8.1.502-507.2024
Abstract
Hyperprolactinemia is an increase in fasting levels of the hormone prolactin above 20 ng/ml in men
and above 25 ng/ml in women. Hyperprolactinemia occurs more often in women of reproductive age,
with a percentage of 9 – 17%. The etiology of hyperprolactinemia can occur due to abnormal pituitary
secretions, systemic disease, use of drugs, damage to the hypothalamus-pituitary axis. A 33-year old
female patient came to the FER Polyclinic at M. Djamil Hospital with complaints of not menstruating
for the past 2 months. Irregular menstruation since 15 years ago, menstruation 2-3 times in 6 months,
irregular cycle for 7-8 days. The patient also complained of a fluid like breast milk coming out of the
breast for 5 years, initially the fluid came out in a trickle and then gradually reduced and now the fluid
comes out occasionally if the breast is squeezed. From the supporting examinations carried out, it was
found that the prolactin hormone level in this patient was 134.53, and the results of the MRI
examination showed a mass measuring 1.05x1.12x0.5 mm, which was diagnosed as secondary
amenorrhea, hyperprolactinemia, and suspected pituitary microadenoma. The patient will be
monitored for general condition and vital signs, as well as consultations with colleagues involved, such
as consultations to the Internal Medicine section, Endocrinology, Metabolic and Diabetes Subdivision.
Keywords
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Majumdar A, Mangal NS. Hyperprolactinemia. J Hum Reprod Sci. 2013;6(3):168-175.
doi:10.4103/0974-1208.121400
Molitch ME, Drummond J, Korbonits M. A Service of the National Library of Medicine.
MDText.com, Inc; 2012.
Melmed S, Casanueva FF, Hoffman AR, et al. Diagnosis and treatment of hyperprolactinemia: An
endocrine society clinical practice guideline. Journal of Clinical Endocrinology and Metabolism.
;96(2):273-288. doi:10.1210/jc.2010-1692
Wang AT, Mullan RJ, Lane MA, et al. Treatment of hyperprolactinemia: A systematic review and
meta-analysis. Syst Rev. 2012;1(1). doi:10.1186/2046-4053-1-33
Vroonen L, Daly AF, Beckers A. Epidemiology and Management Challenges in Prolactinomas.
Neuroendocrinology. 2019;109(1):20-27. doi:10.1159/000497746ed
Molitch ME. Diagnosis and treatment of pituitary adenomas: A review. JAMA - Journal of the
American Medical Association. 2017;317(5):516-524. doi:10.1001/jama.2016.19699
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