PERITONEAL TUBERCULOSIS IN YOUNG AGE LADY MIMICKING GYNECOLOGY MALIGNANCY : A CASE REPORT

Lusi Jelita Sari(1*), Puja Agung Antonius(2), Syamel Muhammad(3)

(1) Obstetrics and Gynecology Department, Faculty of Medicine, Universitas Andalas, Padang
(2) Oncology Ginecology Division of Obstetrics and Gynecology Department, Faculty of Medicine Universitas Andalas, Padang
(3) Oncology Ginecology Division of Obstetrics and Gynecology Department, Faculty of Medicine Universitas Andalas, Padang
(*) Corresponding Author

DOI: https://doi.org/10.25077/aoj.8.1.653-659.2024

Abstract


Background : Peritoneal tuberculosis is one of the most challenging forms of extrapulmonary

tuberculosis to diagnose. Extrapulmonary TB is very difficult to diagnose because of its non-

specific signs and symptoms, thus it sometimes leads to a diagnosis of gynaecological

malignancy such as advanced ovarian carcinoma.

Case Report : A teenage girl, 12 years old, with a chief complaint of intermittent abdominal

pain since the last 1 month. There was no history of an enlarged abdomen, fever and weight

loss. Ultrasound examination revealed an irregular adnexal mass suggesting an ovarian

malignancy with other possibilities of an infectious process. Diagnostic laparoscopy and

peritoneal biopsy were performed on the patient. Intraoperatively, multiple friable nodular-

mylar peritoneal masses with abdominopelvic attachments and fibrin fibres and white vesicles

were found on the entire surface of the genitalia, peritoneum, and intestines. A mass biopsy

was performed with histopathological results showing peritoneal tuberculosis. Currently, the

patient is undergoing anti-tuberculosis drugs (OAT) treatment.

Discussion : The diagnosis of this disease is difficult to establish. Symptoms are highly

variable and non-specific and can lead to the wrong tumour pathology. The clinical

characteristics are dominated by changes in general condition, abdominal pain and transit

disorders, as well as masses (20 to 25%). The gold standard for definitive PTB diagnosis

remains laparoscopy with peritoneal biopsy and subsequent pathological or microbiological

confirmation. Yellow/white nodules in the peritoneum observed on the patient's laparoscopic

images are the hallmark of wet peritoneal TB. Omental thickening and abdominal cocoon with

matted small bowel are other classic laparoscopic findings for peritoneal TB.

Conclusion : PTB has similar characteristics to peritoneal carcinoma, which makes diagnosis

difficult for clinicians. Early and correct diagnosis of PTB helps to initiate medical management

quickly and helps reduce morbidity and mortality.


Keywords


peritoneal tuberculosis, gynecological malignancy, young age

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References


Koff A, Azar MM. Diagnosing peritoneal tuberculosis. BMJ Case Rep. 2020 Feb;13(2).

Wu DC, Averbukh LD, Wu GY. Diagnostic and Therapeutic Strategies for Peritoneal

Tuberculosis: A Review. J Clin Transl Hepatol. 2019 Jun;7(2):140–8.

Purbadi S, Indarti J, Winarto H, Putra AD, Nuryanto KH, Utami TW, et al. Peritoneal

tuberculosis mimicking advanced ovarian cancer case report: Laparoscopy as

diagnostic modality. Int J Surg Case Rep [Internet]. 2021;88:106495. Available from:

https://www.sciencedirect.com/science/article/pii/S2210261221009974

Bimantoro AS, Maimunah U. Diagnosis challenges of a patient with peritoneal

tuberculosis masquerading as ovarian malignancy: a case report. Bali Med J [Internet].

Dec 1;11(3 SE-CASE REPORT):1849–54. Available from:

https://www.balimedicaljournal.org/index.php/bmj/article/view/3892

Alrashed RF, Alkhuwaylidi AA, Aldashash KA, Albati NA, Algarni AA, Almodhaiberi H,

et al. Peritoneal Tuberculosis in a Young Healthy Male Resembling Intra-Abdominal

Malignancy. Vol. 13, Cureus. United States; 2021. p. e20677.

Terras Alexandre A, Raimundo S, Pinto C. Peritoneal tuberculosis – A rare diagnosis.

Pulmonology [Internet]. 2017;23(3):172–3. Available from:

https://www.journalpulmonology.org/en-peritoneal-tuberculosis-a-rare-articulo-

S2173511517300350

Zaslavsky J, Mulugeta-Gordon L, Vasko I, Presenza T, Scattergood E, Meislich D, et

al. Tuberculous peritonitis in children: Two case reports highlighting the important role

of imaging. Radiol Case Reports [Internet]. 2018;13(4):862–6. Available from:

https://www.sciencedirect.com/science/article/pii/S193004331830147X

ELmajdoubi H, EL Yahiyaoui M, Baiss M, Bouzroud M, Aboulfeth EM, Najih M, et al.

Abdominopelvic Mass Revealing Tuberculosis in a Young Woman. Mantas D, editor.

Case Rep Surg [Internet]. 2021;2021:7257533. Available from:

https://doi.org/10.1155/2021/7257533

Sen D, Brunton J, Melchior L, Klein D, Levy GH, Wainscoat B, et al. Peritoneal

tuberculosis: A case report on a rare cause of tumor marker elevation. Vol. 28, Case

reports in women’s health. Netherlands; 2020. p. e00264.

Maheshwari A, Gupta S, Rai S, Rekhi B, Kelkar R, Shylasree TS, et al. Clinical and

Laboratory Characteristics of Patients with Peritoneal Tuberculosis Mimicking

Advanced Ovarian Cancer. South Asian J cancer. 2021 Apr;10(2):102–6.

Rinaldi I, Muthalib A, Gosal D, Wijayadi T, Sutedja B, Setiawan T, et al. Abdominal

Tuberculosis Mimicking Ovarian Cancer: A Case Report and Review of the Literature.

Vol. 15, International medical case reports journal. New Zealand; 2022. p. 169–85.


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