• Hardi Cahyo Utomo Obstetrics and Gynecology Department, Faculty of Medicine, Universitas Andalas, Padang
  • Haviz Yuad Fertility Endocrine Reproduction Division of Obstetrics and Gynecology Department, Faculty of Medicine Universitas Andalas, Padang
  • Ida Rahmah Burhan Obstetrics and Gynecology Department, Faculty of Medicine Universitas Andalas, Padang



Adolescent, PCOS, Vitamin D


PCOS is characterized by increased ovarian and adrenal androgen secretion,

hyperandrogenic symptoms such as hirsutism, acne and/or alopecia, menstrual irregularities,

and polycystic ovaries. The prevalence of PCOS in 2016 was 6−21% of reproductive age

worldwide. PCOS is the most common female endocrine disorder with a prevalence of around

4-6% in women of reproductive age in Indonesia. Vitamin D deficiency can increase PCOS

symptoms. The research design was cross-sectional. The study was conducted at SMA N 7,

SMA N 8 and SMA N 13 Padang in Koto Tangah District in May-August 2022. The research

sample was high school students who experienced menstrual cycle disorders and were willing

to agree to informed consent for the study with a sample size of 59 respondents. Vitamin D

levels were examined using the 25-Hydroxyvitamin D ELISA Kit. Data were analyzed by chi-

square test. The results showed that 86.4% of respondents experienced vitamin D deficiency.

Statistically there was a relationship between PCOS in adolescents accompanied by

hyperandrogens and vitamin D levels, there was a relationship between PCOS in adolescents

accompanied by obesity and vitamin D levels, there was no relationship between PCOS in

adolescents accompanied by acanthosis nigrican and vitamin D levels, and there was no

relationship between PCOS in adolescents accompanied by hyperandrogens, obesity and

acanthosis nigrican with vitamin D levels in SMA Koto Tangah District Padang in 2022. The

conclusion of this study is that there is a relationship between PCOS in adolescents

accompanied by hyperandrogens and vitamin D levels and there is a relationship between

PCOS in adolescents accompanied by obesity and vitamin D levels. .


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