Comparison Of Lactobacillus Plantarum, Lactobacillus Mucosae And Lactobacillus Farciminis Bacteria Between Polycystic Ovary Syndrome And Non Polycystic Ovary Syndrome Students At Medical Faculty Of Andalas University

Authors

  • Mentari Faisal Putri Department of Obstetrics and Gynecology, Faculty of Medicine, Andalas University/Dr. M. Djamil Hospital, Padang
  • Haviz Yuad Endocrinology and Reproductive Fertility Division, Department of Obstetrics and Gynecology, Faculty of Medicine, Andalas University/Dr. M. Djamil Hospital, Padang
  • Andani Eka Putra Center for Infectious Disease Diagnostics and Research, Faculty of Medicine, Andalas University/Dr. M. Djamil Hospital, Padang

DOI:

https://doi.org/10.25077/aoj.8.2.732-745.2024

Keywords:

Polycystic Ovary Syndrome, Gut Microbiota

Abstract

Background: Polycystic Ovary Syndrome (PCOS) is a disorder characterized by hyperandrogenism, ovulatory dysfunction, and morphological features of polycystic ovaries. It is associated with insulin resistance and hyperinsulinemia. Gut microbial dysbiosis plays a role in PCOS, which is associated with insulin resistance, hyperandrogenism, chronic inflammation, and metabolic syndrome. PCOS treatment with Probiotics maintains the stability and diversity of the gut microbiome.

Objective: To determine the comparison of Lactobacillus plantarum, Lactobacillus mucosae, and Lactobacillus farciminis Bacteria Between Polycystic Ovary Syndrome and Non Polycystic Ovary Syndrome Students at the Medical Faculty of Andalas University.

Method: This research was an analytic observational study using a cross-sectional method conducted on female students with Polycystic Ovary Syndrome and Non-Polycystic Ovary Syndrome at the Medical Faculty of Andalas University.

Results: Bivariate analysis of microbiota comparison of female students with PCOS and without PCOS, Mann-Whitney Test on L.mucosae (p=0.774), while Independent T-Test analysis on L.farciminis (p=0.006).

Conclusion: There is a decrease in microbiota L. Mucosae in female students with PCOS, but there is no significant difference. There is a significant comparison in the number of microbiota L.farciminis in female students with and without PCOS at FK Unand.

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Published

2024-07-25

Issue

Vol. 8 No. 2 (2024)

Section

RESEARCH ARTICLE

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Copyright (c) 2024 Mentari Faisal Putri, Haviz Yuad, Andani Eka Putra

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Andalas Obstetrics and Gynecology Journal (AOJ) is published under the terms of the Creative Commons Attribution 4.0 International License. This license permits anyone to copy and redistribute this material in any form or format, compose, modify, and make derivatives of this material for any purpose, including commercial purposes, as long as they credit the author for the original work.