Comparison Of Lactobacillus Plantarum, Lactobacillus Mucosae And Lactobacillus Farciminis Bacteria Between Polycystic Ovary Syndrome And Non Polycystic Ovary Syndrome Students At Medical Faculty Of Andalas University

Authors

  • Mentari Faisal Putri Department of Obstetrics and Gynecology, Faculty of Medicine, Andalas University/Dr. M. Djamil Hospital, Padang
  • Haviz Yuad Endocrinology and Reproductive Fertility Division, Department of Obstetrics and Gynecology, Faculty of Medicine, Andalas University/Dr. M. Djamil Hospital, Padang
  • Andani Eka Putra Center for Infectious Disease Diagnostics and Research, Faculty of Medicine, Andalas University/Dr. M. Djamil Hospital, Padang

DOI:

https://doi.org/10.25077/aoj.8.2.732-745.2024

Keywords:

Polycystic Ovary Syndrome, Gut Microbiota

Abstract

Background: Polycystic Ovary Syndrome (PCOS) is a disorder characterized by hyperandrogenism, ovulatory dysfunction, and morphological features of polycystic ovaries. It is associated with insulin resistance and hyperinsulinemia. Gut microbial dysbiosis plays a role in PCOS, which is associated with insulin resistance, hyperandrogenism, chronic inflammation, and metabolic syndrome. PCOS treatment with Probiotics maintains the stability and diversity of the gut microbiome.

Objective: To determine the comparison of Lactobacillus plantarum, Lactobacillus mucosae, and Lactobacillus farciminis Bacteria Between Polycystic Ovary Syndrome and Non Polycystic Ovary Syndrome Students at the Medical Faculty of Andalas University.

Method: This research was an analytic observational study using a cross-sectional method conducted on female students with Polycystic Ovary Syndrome and Non-Polycystic Ovary Syndrome at the Medical Faculty of Andalas University.

Results: Bivariate analysis of microbiota comparison of female students with PCOS and without PCOS, Mann-Whitney Test on L.mucosae (p=0.774), while Independent T-Test analysis on L.farciminis (p=0.006).

Conclusion: There is a decrease in microbiota L. Mucosae in female students with PCOS, but there is no significant difference. There is a significant comparison in the number of microbiota L.farciminis in female students with and without PCOS at FK Unand.

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Published

2024-07-25

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Section

RESEARCH ARTICLE