The use of Fresh Amnion Membranes on Scar Incision of Caesarean Section

Syahredi Syaiful Adnani(1*), Hafni Bachtiar(2)

(1) Sub Division of Social Obstetrics and Gynecology, Obstetrics and Gynecology Department, Faculty of Medicine, Andalas University, Dr. M. Djamil Central General Hospital Padang
(2) Public Health Department, Faculty of Medicine, Andalas University Padang
(*) Corresponding Author



In the last few decades, the incidence of caesarean section is increasing in the world, especially in Indonesia. One of the way to treat tissue scar is through biologic and synthetic dressing where nowadays, amnion has been used as biologic dressing frequently. This study was conducted to determine the effect of the use of fresh amniotic membrane on wound incision Caesarean section compared with Caesarean section incision wound covered using regular gauze bandages and fixated with plaster in RS. Dr. Reksodiwiryo Padang. The design of this study is an experimen-tal study with Post test design with control group design. Sampling was done using a formula consecutive sampling two different test samples obtained an average of 72 people for each group. The analysis used include univariate and bivariate analyzes. The average wound healing time the difference was statistically significant (p value <0.05) in the treatment and control groups. There was highly significant difference in the proportion of local infection on day 3 between the treatment and control groups (p value <0.05). There were very significant differences in the proportion of local allergic reactions at day 3, and 5 between the treatment and control group (p <0.05). There are significant differences in terms of the cost of care per day between treatment and control groups (p <0.05). From this study, the average wound healing time has a very significant difference.

Keywords: Fresh Amniotic Membrane, Wound Cesarean Section, Wound Healing

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Hamilton BE, et al. Births: preliminary data for 2010. National vital stat Rep. 2011.

Mallef Mallefet et P, et al. Mechanism involved in wound hhealing. Biomedical Scientist.2008.

Ganatra MA. Amniotic membrane in Surgery Jourmal of Pakistan Medical Association. Vol. 53, 2003.

Menkher Manjas, et al. Clinical Application of Irradiated Amnion Grafts. Allograft Procurement and Processing and Transplantation. World Scientific. 2010.

Miki T., Storm S.C, 2008. Amnion Derived Pluripotent/ Multipotent Stem Cells in Stem Cell Rev. 2006; 2(2):133-42,http://www. ncbi.nlm.nih. gov/pubmed/1723759, 1 juni 2012

Cunningham FG, Leveno KJ, Bloom S. Implantation, Embryogenesis, and Placental development in William Obstetrics. Mc Graw Hill, edisi 23. USA. 2010; 65-68

Steed DL, Trumpower C, Duffy D, etc. Amnion derived Cellular Cytokine Solution. NCBI. 2008. pubmed/20395817, 31 mei 2012

Menkher M, Jefri H, Salmah A. Majalah kedokteran Indonesia: Penggunaan Krim amnion pada penyembuhan Luka Sayatan Tikus Winstar. Bagian patologi anatomi Fk Universitas Andalas. Padang. 2010.

Toda A, et al. The Potential of Amniotic Membran/aAmnion-derived cells for regeneration of various tissue. Journal of Pharmacological sciences 105. 2008.


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